Martonová, Denisa
Dr.-Ing. Denisa Martonová
posdoctoral researcher
Immerwahrstrasse 1
91058 Erlangen
Germany
Department of Mechanical Engineering
Institute of Applied Dynamics (LTD, Prof. Leyendecker)
Immerwahrstrasse 1
91058 Erlangen
Germany
- Phone number: +49 9131 85-61013
- Fax number: +49 9131 85-61011
- Email: denisa.martonova@fau.de
- Website: https://www.ltd.tf.fau.de/denisa-martonova
- 2011 – 2014 B.Sc. in Molecular Medicine, University of Regensburg
- 2013 – 2016 B.Sc. in Mathematics, University of Regensburg
- 2016 – 2018 M.Sc. in Mathematics, University of Regensburg
- 2019 – 2023 Dr.-Ing. in Mechanical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg
- 2022 research stay at Queensland University of Technology, Australia
- 2023 research stay at Stanford University, USA
- 2024 – postdoctoral researcher, Institute of Applied Dynamics, Friedrich-Alexander-Universität Erlangen-Nürnberg
theses
2024
- Martonová D.:
Computational modelling and simulation of rat heart electromechanics – from (smoothed) finite element methods towards a ligand-receptor model (Dissertation, 2024)
URL: https://www.ltd.tf.fau.de/files/2024/05/dissertation-denisa-martonova.pdf
2018
reviewed journal publications
2024
- Martonová D., Peirlinck M., Linka K., Holzapfel GA., Leyendecker S., Kuhl E.:
Automated model discovery for human cardiac tissue: Discovering the best model and parameters
In: Computer Methods in Applied Mechanics and Engineering 428 (2024), Article No.: 117078
ISSN: 0045-7825
DOI: 10.1016/j.cma.2024.117078
2023
- Holz D., Martonová D., Schaller E., Duong MT., Alkassar M., Weyand M., Leyendecker S.:
Transmural fibre orientations based on Laplace-Dirichlet-Rule-Based-Methods and their influence on human heart simulations
In: Journal of Biomechanics (2023), Article No.: 111643
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2023.111643 - Martonová D., Holz D., Duong MT., Leyendecker S.:
Smoothed finite element methods in simulation of active contraction of myocardial tissue samples
In: Journal of Biomechanics (2023)
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2023.111691 - Martonová D., Lavaill M., Forwood MR., Robling A., Cooper DML., Leyendecker S., Pivonka P.:
Effects of PTH glandular and external dosing patterns on bone cell activity using a two-state receptor model—Implications for bone disease progression and treatment
In: PLoS ONE (2023)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0283544
2022
- Martonová D., Holz D., Brackenhammer D., Weyand M., Leyendecker S., Alkassar M.:
Support Pressure Acting on the Epicardial Surface of a Rat Left Ventricle — A Computational Study
In: Frontiers in Cardiovascular Medicine 9 (2022)
ISSN: 2297-055X
DOI: 10.3389/fcvm.2022.850274 - Martonová D., Holz D., Seufert J., Duong MT., Alkassar M., Leyendecker S.:
Comparison of stress and stress–strain approaches for the active contraction in a rat cardiac cycle model
In: Journal of Biomechanics 134 (2022), Article No.: 110980
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2022.110980
2021
- Holz D., Duong MT., Martonová D., Alkassar M., Leyendecker S.:
A Transmural Path Model Improves the Definition of the Orthotropic Tissue Structure in Heart Simulations
In: Journal of Biomechanical Engineering-Transactions of the Asme 144 (2021), p. 031002 (10 pages)
ISSN: 0148-0731
DOI: 10.1115/1.4052219 - Martonová D., Alkassar M., Seufert J., Holz D., Duong MT., Reischl B., Friedrich O., Leyendecker S.:
Passive mechanical properties in healthy and infarcted rat left ventricle characterised via a mixture model
In: Journal of the Mechanical Behavior of Biomedical Materials 119 (2021), Article No.: 104430
ISSN: 1751-6161
DOI: 10.1016/j.jmbbm.2021.104430 - Martonová D., Holz D., Duong MT., Leyendecker S.:
Towards the simulation of active cardiac mechanics using a smoothed finite element method
In: Journal of Biomechanics 115 (2021), p. 110153
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2020.110153
conferences and proceedings
2024
- Leyendecker S., Martonová D., Stavole M.:
Structure preserving neural network-based methods — Euler’s elastica and cardiac model discovery
conference, NUMDIFF-17 Conference on the Numerical Solution of Differential and Differential-Algebraic Equations (Halle, 2024-09-09 - 2024-09-13) - Martonová D., Peirlinck M., Linka K., Holzapfel GA., Leyendecker S., Kuhl E.:
Automated model discovery for human cardiac tissue
conference, Netzwerktagung der Alexander von Humboldt Stiftung (Erlangen, 2024-11-21) - Martonová D., Peirlinck M., Linka K., Holzapfel GA., Leyendecker S., Kuhl E.:
Constitutive neural networks for model discovery of myocardial tissue
conference, CMBBE 2024 SYMPOSIUM, 19th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (Vancouver, 2024-07-30 - 2024-08-01)
2023
- Martonová D., Holz D., Duong MT., Leyendecker S.:
Smoothed finite element methods in modelling and simulation of active cardiac contraction
conference, 18th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (Paris, 2023-05-03 - 2023-05-05)
2022
- Holz D., Martonová D., Schaller E., Duong MT., Alkassar M., Leyendecker S.:
The influence of the orthotropic tissue in an electromechanical heart model
conference, 27th Congress of the European Society of Biomechanics (Porto, 2022-06-26 - 2022-06-29)
2021
- Holz D., Duong MT., Martonová D., Alkassar M., Leyendecker S.:
Discontinuous Galerkin-based approach to define orthotropic tissue structure in computational heart models
conference, International Conference on Computational Biomechanics (Paris, 2021-09-20 - 2021-09-21) - Martonová D., Alkassar M., Seufert J., Holz D., Duong MT., Reischl B., Friedrich O., Leyendecker S.:
Characterisation of passive mechanical properties in healthy and infarcted rat myocardium
conference, GAMM Annual Meeting (Kassel, 2021-03-15 - 2021-03-19) - Martonová D., Alkassar M., Seufert J., Holz D., Duong MT., Reischl B., Friedrich O., Leyendecker S.:
Influence of passive mechanical properties in healthy and infarcted rat myocardium on the cardiac cycle
GAMM Annual Meeting (Kassel, 2021-03-15 - 2021-03-19)
In: Proc. Appl. Math. Mech. (PAMM) 2021
DOI: 10.1002/pamm.202100054
2019
- Holz D., Duong MT., Martonová D., Alkassar M., Dittrich S., Leyendecker S.:
Möglichkeiten und Perspektiven der Modellierung und Simulation
Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie (Wiesbaden, 2019-02-16 - 2019-02-19)
further publications
-
Smoothed finite element methods in modelling and simulation of cardiac electromechanics
(Third Party Funds Single)
Term: 2022-04-01 - 2024-03-31
Funding source: Deutsche Forschungsgemeinschaft (DFG) -
Establishment of a heart support system as a contractile membrane based on the pericardium
(Third Party Funds Single)
Term: 2016-05-01 - 2022-07-15
Funding source: StiftungenThis projectcontains the establishment of a heart support system as a contractile membrane based on the pericardium to minimize theconsequences of severe heart disease and to maintain proper cardiacfunction. The project is a research cooperation between the Institute ofApplied Dynamics and the Pediatric Cardiology at the Friedrich-Alexander-Universität Erlangen-Nürnberg and is funded by the Klaus Tschira Foundation.
The project includes the study ofcardiac function under pathological and normal conditions by developing computer models of the heart, which are validated with experimental data ofpediatric cardiology of the University of Erlangen Nuremberg. The clinicalmeasurements and experimental data, as well as the simulation model are basedon rat hearts. Subsequently, a cardiac support system based on a membrane is to be designed to improve or at least maintain heart function under pathological conditions.
In particular at the Institute of Applied Dynamics, we are focusing on the development of theunderlying computational heart model including the anatomy, morphology,electrophysiology and also the fluid-structure interaction to be able to buildup the optimized heart support system but also to better understand thefunction of the heart and thus to predict or early detect cardiac dysfunctions andbring new treatments to the clinic.